Zopiclone

Description

What is Zopiclone?

Zopiclone is a prescription-only sleeping tablet used for the short-term treatment of insomnia. It belongs to a group of medicines known as “Z-drugs” (non-benzodiazepine hypnotics), which act on the brain to promote sleep.

It is commonly prescribed when sleep problems are severe, disabling, or causing significant distress.

What is Zopiclone Used For?

Zopiclone is used to treat short-term sleep disorders, including:

• Difficulty falling asleep
• Waking up frequently during the night
• Early morning waking
• Severe or temporary insomnia caused by stress or anxiety

It is typically prescribed for short durations (usually 2–4 weeks) to reduce the risk of dependence.

How Does Zopiclone Work?

Zopiclone works by enhancing the effects of GABA (gamma-aminobutyric acid), a calming chemical in the brain that slows down nerve activity.

This results in:

• Faster sleep onset
• Longer sleep duration
• Fewer night-time awakenings
• Improved sleep quality

Its effects usually begin within 30–60 minutes, helping you fall asleep quickly.

How to Take Zopiclone

Always take Zopiclone exactly as prescribed by your doctor.

General guidance:

• Take just before bedtime
• Swallow the tablet whole with water
• Ensure you can get 7–8 hours of uninterrupted sleep
• Take only once per night

Important:

• Do not take another dose during the same night
• Avoid alcohol while taking Zopiclone
• Do not use for longer than prescribed

Dosage Information

Dosage depends on your individual needs and medical history.

• Typical adult dose: 7.5 mg at bedtime
• Elderly or sensitive patients: Lower dose (e.g. 3.75 mg)
• Patients with liver or kidney issues: Dose adjustments may be required

Your prescriber will determine the safest and most effective dose for you.

Possible Side Effects

Like all medicines, Zopiclone may cause side effects.

Common side effects:

• Bitter or metallic taste in the mouth
• Drowsiness the next day
• Dry mouth
• Dizziness

Less common but serious effects:

• Memory problems
• Sleepwalking or unusual behaviour during sleep
• Mood changes or confusion
• Allergic reactions

If you experience unusual behaviours or severe side effects, seek medical advice immediately.

Warnings and Precautions

Zopiclone is a controlled medication due to its potential for dependence and misuse.

Before taking Zopiclone, inform your doctor if you:

• Have a history of substance misuse
• Have breathing problems (e.g. sleep apnoea)
• Have liver or kidney disease
• Are pregnant or breastfeeding
• Have mental health conditions

Safety advice:

• Avoid driving the next day if you feel drowsy
• Do not combine with alcohol or sedatives
• Use only for short-term treatment

Drug Interactions

Zopiclone may interact with other medications that affect the central nervous system.

These include:

• Benzodiazepines
• Antidepressants
• Antihistamines
• Opioid painkillers

Combining these can increase the risk of excessive sedation, impaired coordination, and breathing difficulties.

Dependence and Withdrawal

Zopiclone can cause physical and psychological dependence, especially if used for longer than recommended.

Withdrawal symptoms may include:

• Rebound insomnia
• Anxiety or irritability
• Sweating
• Tremors

To minimise risks:

• Use for short durations only
• Follow your doctor’s guidance when stopping

Storage Instructions

• Store below 25°C
• Keep in original packaging
• Protect from moisture

Keep out of reach of children